ACES stands for the "Anal Cancer Examination Study". The purpose of the research project is to determine if the introduction of yearly anal examinations will detect anal cancer earlier than it has been diagnosed previously.

When anal cancer is detected earlier, when it is smaller, it is easier to treat and the chance of cure is higher.

Men who are 35 years and over with HIV and who have sex with men can participate and are asked to:

• Have an annual anal examination by their chosen doctor for 2 years
• Complete a questionnaire:-

  - When commencing

  - Two weeks later

  - Annually for 2 years

• Give permission to access medical details from the cancer registry
• Give permission to review medical files
• Have 2 anal swabs (by the doctor or self-collect) – one at baseline and one 2 years later to check for Human Papillomavirus (the virus which sometimes can be associated with anal cancer).
• Agree to receive an SMS or email reminder to book an examination appointment with their doctor, when it is due.